This book brings together basic scientists or clinicians from a variety of different backgrounds – immunology, infectious diseases or critical care – who share a common interest in understanding the changes that occur in immune responses in sepsis. It provides an up-to-date and unrivalled synthesis of current research in this rapidly developing field.
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The World’s leading experts provide all the ‘Essentials’ needed to manage patients in the office, on the ward and in the ICU. HIV Essentials 2011 incorporates the latest clinical guidelines into a step-by-step guide to the diagnosis, evaluation, management and prevention of HIV infection and its complications. Topics include: HIV diagnosis, evaluation, treatment and prevention; Opportunistic infections and other HIV Complications; Treatment of HIV and pregnancy; Antiretroviral drug summaries; Post-exposure Prophylaxis; New section to each drug summary called “How Supplied” describes the commercially available dosage forms for all the ARV’s
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How sexual risk is negotiated betwen partners is an area of considerable theoretical interest, with the dominant models of analysis focusing on individual decisions to engage in sexual behaviour and relying on “rational” decision-making. This work, based on the findings from work coordinated by the Centre d’Etudes Sociologiques in Brussels, offers a social critique of the theories and perspectives which have currently been brought to bear in the study of sexual risk behaviour and HIV. Leading European researchers offer a conceptual framework for analysis based on sexual interactions and their social context. The practical relevance of new perspectives on sexual behaviour in the context of HIV/AIDS prevention is also discussed.
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Based on a symposium covering latest research, this volume contains contributions by international experts. They investigate the role that viruses play in certain diseases, and include discussions of animal models and human trials. Some of the chapters cover specifically: streptococci and rheumatic heart disease, Epstein-Barr infection and cancer, and molecular mimicry and autoimmune disease.
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HIV Essentials 2010 incorporates the latest clinical guidelines into a step-by-step guide to the diagnosis, evaluation, management and prevention of HIV infection and its complications. Topics include: HIV diagnosis, evaluation, treatment and prevention; Opportunistic infections and other HIV Complications; Treatment of HIV and pregnancy; Antiretroviral drug summaries; Post-exposure Prophylaxis; New section to each drug summary called “How Supplied” describes the commercially available dosage forms for all the ARV’s
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The preclinical rationale for whole body hyperthermia is scientifically sound. Realizing the potential of this new modality to be a useful cancer therapy requires further basic research and controlled clinical trials. Thistext provides a foundation of knowledge to evaluate and initiate future studies. In this regard, the authors provide the first comprehensive review of the use of whole body hyperthermia to enhance the antineoplastic activityof ionizing irradiation, chemotherapy and immunotherapy. Contents include a detailed summary and analysis of fundamental principles as well asclinical and laboratory experience. For the clinical or laboratory researcher, useful descriptions of relevant animal models and conceptual aspects of in vitro systems are provided. The biophysics and methodologies for inducing systemic hyperthermia are also fully described. Non-oncological uses of whole body hyperthermia, as well as data relevant to better understanding of the physiological responses to fever, are discussed. It is anticipated that this substantial store of knowledge should prove a key resource for understanding and utilizingthis emerging clinical treatment modality.
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The World’s Leading Experts Provide All The ‘Essentials’ Needed To Manage Patients In The Office, On The Ward, And In The ICU. Completely Revised And Updated, HIV Essentials 2012 Incorporates The Latest Clinical Guidelines Into A Step-By-Step Guide To The Diagnosis, Evaluation, Management, And Prevention Of HIV Infection And Its Complications. Topics Include: Opportunistic Infections And Other HIV Complications, Treatment Of HIV And Pregnancy, Antiretroviral Drug Summaries, Post-Exposure Prophylaxis, As Well As Commercially Available Dosage Forms For All Arvs. New To HIV Essentials 2012: â?¢ 2011 DHHS Guidelines â?¢ 2011 Pregnancy Guidelines â?¢ New Drugs: Edurant, Complera, Incivek, Victrelis, And More.
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The immune system has evolved in large part to enable organisms to resist microbial infection. Microorganisms have long been used as experimental tools by immunologists, and the study of the immune response to viruses and bacteria has contributed much to our understanding of basic immunological mechanisms.
There are also important practical and clinical reasons for attempting to understand the immunology of infections — these include the rational design of vaccines, the pathogenesis of infectious diseases, the advent of AIDS, the rise in drug-resistant mycobacterial infections and the recognition of the infectious aetiology of peptic ulcer disease.
The contributors to this book are all chosen for their active involvement and expertise in the fields. It bridges the divide between basic immunological research and clinical practice.
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The immune system has evolved in large part to enable organisms to resist microbial infection. Microorganisms have long been used as experimental tools by immunologists, and the study of the immune response to viruses and bacteria has contributed much to our understanding of basic immunological mechanisms.
There are also important practical and clinical reasons for attempting to understand the immunology of infections — these include the rational design of vaccines, the pathogenesis of infectious diseases, the advent of AIDS, the rise in drug-resistant mycobacterial infections and the recognition of the infectious aetiology of peptic ulcer disease.
The contributors to this book are all chosen for their active involvement and expertise in the fields. It bridges the divide between basic immunological research and clinical practice.
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“Design Considerations for Evaluating the Impact of PEPFAR” is the summary of a 2-day workshop on methodological, policy, and practical design considerations for a future evaluation of human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) interventions carried out under the President’s Emergency Plan for AIDS Relief (PEPFAR), which was convened by the Institute of Medicine (IOM) on April 30 and May 1, 2007.Participants at the workshop included staff of the U.S. Congress; PEPFAR officials and implementers; major multilateral organizations such as The Global Fund to Fight AIDS, Malaria, and Tuberculosis (The Global Fund), the Joint United Nations Programme on HIV/AIDS (UNAIDS), and the World Bank; representatives from international nongovernmental organizations; experienced evaluation experts; and, representatives of partner countries, particularly the PEPFAR focus countries. The workshop represented a final element of the work of the congressionally mandated IOM Committee for the Evaluation of PEPFAR Implementation, which published a report of its findings in 2007 evaluating the first 2 years of implementation, but could not address longer term impact evaluation questions.
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